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1.
Artigo | IMSEAR | ID: sea-218713

RESUMO

Background Chronic cough (CC) as the main symptom of eosinophilic esophagitis (EoE), associated or not with other signs of esophageal dysfunction, has been poorly studied. Research the frequency of CC symptoms of EoEObjectives and their characteristics. Comorbidities, adherence to treatment, and evolution. An observational,Methods prospective study. Variables: Epidemiological, demographics, atopic, endoscopic, histological, comorbidities, symptoms, time of evolution, endoscopic phenotype, respiratory function tests. Adherence, response to treatment, complications, and evolution Only 20 patients (5%) with EoE had CC. The mean age:24 years, male 85%. TheResults time of evolution: 5 years. CC: recurrent during the day (never at night), worsened with food intake (during or after), improved when remission EoE and reappeared when active EoE. There were a few severe complications. Conclusion Although the frequency of CC as a symptom in EoE is low, it must be considered, especially if it appears in food intake.

2.
Artigo | IMSEAR | ID: sea-220663

RESUMO

Background. Eosinophilic esophagitis (EoE) is characterized by dysphagia and food impactions in adults, gastroesophageal re?ux disease (GERD) symptoms-like in children, and ?15 eosinophils per high power ?eld. Patients have a disease burden due to chronic symptoms and the comorbidities associated. Minor comorbidities in EoE have not been adequately studied in the literature. For this reason, this study aims to investigate the prevalence of atopy, autoimmune, infectious, genetic diseases, and minor others. A prospective observational study in Methods. patients evaluated in a multidisciplinary EoE unit. The most frequent comorbidities were atopic, but the autoimmune Results. and infectious were minorities. In conclusion, in EoE, we must carry out an anamnesis and exhaustive review of the clinical history for the early diagnosis of comorbidities. In patients with atopy, infectious esophagitis, and autoimmune diseases, we will ask about symptoms of GERD or swallowing disorders due to the risk of associated EoE.

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